Adenomyomatosis is a benign (non-cancerous) condition that affects the gallbladder.


It involves the growth of excessive tissue in the gallbladder wall, resulting in the formation of small pouches within the organ. These pouches, known as Rokitansky-Aschoff sinuses, can become distended with bile and lead to a thickening of the gallbladder wall.


While the exact cause of adenomyomatosis remains unclear, it is often associated with conditions such as gallstones, inflammation of the gallbladder, and certain other gallbladder disorders.


Thickening of the gallbladder wall caused by adenomyomatosis can also create diagnostic confusion and raise concern for cancer of the gallbladder in some cases.


Typically, adenomyomatosis is diagnosed incidentally during imaging tests for other conditions or when a gallbladder undergoes microscopic evaluation after it has been removed. Although adenomyomatosis doesn’t usually cause symptoms, it may lead to abdominal pain on some occasions.


The treatment approach for adenomyomatosis depends on the severity of symptoms and the impact on the patient’s quality of life. It also depends on whether there is any diagnostic doubt about gallbladder wall thickening and if gallbladder cancer is suspected.


Asymptomatic cases may not require any specific treatment apart from routine monitoring. For individuals experiencing persistent and bothersome symptoms, several treatment options may be considered:

  1. Cholecystectomy: Surgical removal of the gallbladder is often recommended for individuals with severe or persistent symptoms. This procedure, known as cholecystectomy, can be usually performed using minimally invasive (laparoscopic/ robotic) techniques.
  2. Symptom Management: In cases where surgery is not immediately necessary or feasible, management of symptoms becomes the focus. This may involve the use of pain medications to alleviate any discomfort or pain associated with the condition.
  3. Lifestyle Modifications: Adopting dietary changes such as reducing the consumption of fatty foods may help minimize symptoms and improve overall digestive health.


It is crucial for individuals diagnosed with adenomyomatosis to consult a healthcare professional regularly to monitor any changes in symptoms or progression of the condition. As the condition is generally benign, overall prognosis is favourable, especially with appropriate management and care.

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